Global properties of the mapping between local amino acid sequence and local structure in proteins.
نویسندگان
چکیده
منابع مشابه
Global properties of the mapping between local amino acid sequence and local structure in proteins.
Local protein structure prediction efforts have consistently failed to exceed approximately 70% accuracy. We characterize the degeneracy of the mapping from local sequence to local structure responsible for this failure by investigating the extent to which similar sequence segments found in different proteins adopt similar three-dimensional structures. Sequence segments 3-15 residues in length ...
متن کاملساختار کلاسهایی از حلقه های z- موضعی و c- موضعی the structure of some classes of z-local and c-local rings
فرض کنیمr یک حلقه تعویض پذیر ویکدار موضعی باشدو(j(r رایکال جیکوبسن r و(z(r مجموعه مقسوم علیه های صفر حلقه r باشد.گوییم r یک حلقه z- موضعی است هرگاه j(r)^2=. .همچنین برای یک حلقه تعویض پذیر r فرض کنیم c یک عنصر ناصفر از (z( r باشد با این خاصیت که cz( r)=0 گوییم حلقه موضعی r یک حلقه c - موضعی است هرگاه و{0 و z(r)^2={cو z(r)^3=0, نیز xz( r)=0 نتیجه دهد که x عضو {c,0 } است. در این پایان نامه ساخ...
SUPER- AND SUB-ADDITIVE ENVELOPES OF AGGREGATION FUNCTIONS: INTERPLAY BETWEEN LOCAL AND GLOBAL PROPERTIES, AND APPROXIMATION
Super- and sub-additive transformations of aggregation functions have been recently introduced by Greco, Mesiar, Rindone and v{S}ipeky [The superadditive and the subadditive transformations of integrals and aggregation functions, {it Fuzzy Sets and Systems} {bf 291} (2016), 40--53]. In this article we give a survey of the recent development regarding the existence of aggregation functions with ...
متن کاملLocal sequence-structure correlations in proteins.
Considerable progress has been made in understanding the relationship between local amino acid sequence and local protein structure. Recent highlights include numerous studies of the structures adopted by short peptides, new approaches to correlating sequence patterns with structure patterns, and folding simulations using simple potentials.
متن کاملLocal sequence-structure relationships in proteins
A better understanding of proteins, their structure, function and roles in biological processes is a key step on the way to understand complex living organisms. Whereas experimental determination of the sequential encoding of proteins (amino acid sequence) is easy, finding out the three-dimensional structure of proteins is complicated and costly. As the structure of a protein usually establishe...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1996
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.93.12.5814